https://doi.org/10.15681/KSWE.2026.42.4.386
이정희(Junghee Lee) ; 김민희(Minhee Kim)
N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone (6PPD-Q), a transformation product of the widely used tire antiozonant 6PPD, has become a contaminant of significant environmental concern due to its widespread occurrence, enhanced persistence, and pronounced toxicity. This review synthesizes current knowledge on the formation pathways, environmental fate, global occurrence, and toxicological implications of 6PPD-Q, with an emphasis on its relevance to environmental monitoring, risk assessment, and management strategies. 6PPD continuously enters the environment through tire and road wear particles and is transformed into 6PPD-Q via multiple abiotic and biotic pathways, including ozonation, photooxidation, soil-mediated oxidation, microbial degradation, and atmospheric reactions. Compared to its precursor, 6PPD-Q exhibits greater environmental stability and persistence, particularly in aquatic and soil systems, where it can partition into suspended particles, sediments, and soil organic matter. Global monitoring studies have identified 6PPD-Q in road runoff, stormwater, snowmelt, rivers, groundwater, sediments, soils, and influents and effluents of wastewater treatment plants, often showing pulse-like increases associated with rainfall and snowmelt events. Toxicity data indicate that 6PPD-Q poses severe hazards to sensitive aquatic organisms, especially salmonids, even at ng/L concentrations. Emerging evidence also suggests potential adverse effects on plants, mammals, and humans. Collectively, these findings establish 6PPD-Q as a critical tire-derived transformation product that requires integrated multi-media monitoring and refined risk evaluation. Future research should prioritize standardized monitoring frameworks, chronic and mixture toxicity characterization, and life-cycle-based mitigation strategies to support effective regulation and environmental management of 6PPD-Q.